ҽƽ̨ҽѧ×ÊѶ

×ÊѶÖÐÐÄ>ҽѧ½øÕ¹>¸Îµ¨Íâ¿Æ> Ô¤²â³ÉÄêÖ¬·¾¸ÎµÄ¶ùͯÆÚΣÏÕÒòËØ

Ô¤²â³ÉÄêÖ¬·¾¸ÎµÄ¶ùͯÆÚΣÏÕÒòËØ

ÊÕ²Ø
À´Ô´£ºÒ½Ñ§ÂÛ̳Íø 2016-06-04 07:00

·ÒÀ¼Ò»ÏîÑо¿±íÃ÷£¬³ÉÄêÖ¬·¾¸ÎµÄ¶ùͯÆÚΣÏÕÒòËØΪСÓÚÌ¥Áä¡¢ÒȵºËظßˮƽºÍÌåÖÊÖ¸Êý(BMI)Éý¸ß;ÄÉÈëPNPLA3ºÍTM6SF2»ùÒò±äÒì¼ì²â¿ÉÔöÇ¿¶Ô³ÉÄêÖ¬·¾¸ÎµÄÔ¤²â¡£ÂÛÎÄ5ÔÂ24ÈÕÔÚÏß·¢±íÓÚ¡¶¸ÎÔಡѧÔÓÖ¾¡·(JHepatol)¡£
¸ÃÑо¿ÄÉÈë1980Äê»ùÏßÄêÁäΪ3¡«18ËêµÄ2042ÀýÊÜÊÔÕߣ¬2011ÄêÄ©´ÎËæ·ÃʱÐг¬Éù¸ÎÔàɨÃè¡£³ýÓëÖ¬·¾¸ÎÏà¹ØµÄÉíÌåºÍ»·¾³ÒòËØÍ⣬ÆÀ¹ÀPNPLA3µ¥ºËÜÕËá¶à̬ÐÔ(rs738409)ËùÖµÄÒÅ´«·çÏÕÊÇ·ñÔöÇ¿³ÉÄêÖ¬·¾¸ÎµÄÔ¤²âÄÜÁ¦¡£
½á¹ûÏÔʾ£¬³ÉÄêÖ¬·¾¸ÎµÄ¶ÀÁ¢¶ùͯÆÚÔ¤²âÒòËØΪСÓÚÌ¥Áä[±ÈÖµ±È(OR)Ϊ1.71]¡¢PNPLA3±äÒì(OR1.63)¡¢TM6SF2±äÒì(OR1.57)¡¢BMIÉý¸ß(OR1.30)ºÍÒȵºËظßˮƽ(OR1.25)¡£¶ùͯÆÚѪѹ¡¢ÌåÓý¶ÍÁ¶¡¢C-·´Ó¦µ°°×¡¢ÎüÑÌ¡¢ÑªÖ¬Ë®Æ½ºÍ¸¸Ä¸Éú»î·½Ê½¶Ô³ÉÈËÖ¬·¾¸Î½øÐÐÔ¤²âÎÞͳ¼ÆѧÒâÒå¡£»ùÓÚ¶ùͯÆÚÄêÁä¡¢ÐÔ±ð¡¢BMI¡¢ÒȵºËØˮƽ¡¢³öÉúÌåÖØ¡¢TM6SF2ºÍPNPLA3µÄ·çÏÕÆÀ¹ÀÔÚÔ¤²âÖ¬·¾¸Î·½ÃæÓÅÓÚ½öÓÃÄêÁä¡¢ÐÔ±ð¡¢BMIºÍÒȵºËØˮƽµÄÔ¤²â·½·¨(P=0.002)¡£

¹Ø¼ü´Ê£º Ö¬·¾¸Î ¶ùͯÆÚ

Ò½ÓÑÆÀÂÛ£¨0ÈËÆÀÂÛ£©

ÄäÃû·¢±í

ÈÈÃżìË÷£ºÌÇÄò²¡ÉËÒ½»ù²ãÒ½Ôº